Chapter: 26
A diffuse reduction of bone mass and x-ray density, more often occurring in post-menopausal females. This is the most common metabolic disease in the world and is the underlying cause of 350,000 vertebral and hip fractures annually in the U.S., costing an estimated 1 billion dollars. Pathogenesis: bone resorption exceeds bone formation to a mild degree over a long period leading to osteopenia. There is no defect in bone mineralization.

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